Louis C. Argenta, M.D.

Recent Publications

• Age-dependent changes in brain hydration and synaptic plasticity Vashisht A, Morykwas M, Hegde AN, Argenta L, McGee MP.. Brain Res. 2018;1680():46-53.
• Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage Carroll DL, Jordan JE, Argenta LC, Morykwas MJ, Wagner WD, inventors; Wake Forest University Health Sciences, assignee.. Germany patent DE 2,313,008. 2017 Apr 12 (patent also held in Austria, France, Netherlands, Switzerland, United Kingdom, and European Patent Office. 2017;():.
• Application of localized sub-atmospheric pressure to the brain and spinal cord Morykwas MJ, Argenta LC, Tatter SB, inventors; Wake Forest University Health Sciences, assignee.. Israel patent IL 206899. 2017 Mar 30. 2017;():.
• Device and method for treating central nervous system pathology Argenta LC, Morykwas MJ, Tatter SB, inventors; Wake Forest University Health Sciences, assignee.. Australia patent AU 2.01E+09. 2017 Apr 20. 2017;():.
• External fixation assembly and method of use Argenta LC, Morykwas MJ, Webb LX, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 9,566,089. 2017 Feb 14. 2017;():.
• Hydration control in brain extracellular matrix: astrocytes, perycites, and fibroblasts adjust their contractile responses to local water activity [abstract] McGee MP, Kearns M, Morykwas M, Argenta L.. Biophys J. 2017;112(3 Suppl 1):437A.
• Structural and mechanical characterization of bioresorbable, elastomeric nanocomposites from poly(glycerol sebacate)/nanohydroxyapatite for tissue transport applications Rosenbalm TN, Teruel M, Day CS, Donati GL, Morykwas M, Argenta L, Kuthirummal N, Levi-Polyachenko N.. J Biomed Mater Res B Appl Biomater. 2016;104(7):1366-1373.
• Ameliorating spinal cord injury in an animal model with mechanical tissue resuscitation Zheng ZL, Morykwas MJ, Tatter S, Gordon S, McGee M, Green H, Argenta LC.. Neurosurgery. 2016;78(6):868-876.
• Local fluid transfer regulation in heart extracellular matrix McGee MP, Morykwas MJ, Jordan JE, Wang R, Argenta LC.. J Physiol Biochem. 2016;72(2):255-268.
• Measuring hydraulic conductance and hydration potential of brain extracellular matrix by osmotic stress [abstract] McGee MP, Morykwas M, Argenta L.. Biophys J. 2016;110(3 Suppl 1):149A-150A.
• Mechanical tissue resuscitation increases neuronal expression of brain-derived neurotrophic factor (BDNF) in traumatic brain injury [abstract] Zheng ZL Morykwas M, Argenta L.. Brain Inj. 2016;30(5-6):675.
• Novel nanofiber-based material for endovascular scaffolds Wang R, Levi-Polyanchenko N, Morykwas M, Argenta L, Wagner WD.. J Biomed Mater Res A. 2015;103(3):1150-1158.
• The use of brainlab navigation in Le Fort III osteotomy Wood JS, Purzycki A, Thompson J, David LR, Argenta LC.. J Craniofac Surg. 2015;26(3):616-619.
• Mechanical tissue resuscitation (MTR): a nonpharmacological approach to treatment of acute myocardial infarction Jordan JE, Pereira BD, Lane MR, Morykwas MJ, McGee M, Argenta LC.. J Card Surg. 2015;30(8):659-667.
• Expanding the phenotype of neural crest cell disorders: hirschsprung disease in branchio-oculo-facial syndrome [abstract] Haldeman-Englert CR, Berry MN, Stamper TH, Jewett T, Argenta LC, Milunsky A.. Am J Med Genet A. 2015;167(8):1702-1703.
• Spine fusion using a soft elastomeric nanofibrous composite of collagen, poly (1,8-octanediol-co-citrate) and chondroitin 6-sulfate [abstract] Wagner W, Morykwas M, Argenta L, Campbell D, Wang R.. FASEB J. 2015;29(Suppl 1):1029.15.
• Correlating heart interstitium structure and function using hydration and Magnetic Resonance Image (MRI) analyses [abstract] McGee MP, Morykwas M, Jordan J, Argenta L.. Biophys J. 2015;108(2 Suppl 1):148A.
• Properties of single electrospun poly (diol citrate)-collagen-proteoglycan nanofibers for arterial repair and in applications requiring viscoelasticity Liu J, Argenta L, Morykwas M, Wagner WD.. J Biomater Appl. 2014;28(5):729-738.
• Mechanical tissue resuscitation protects against myocardial ischemia-reperfusion injury Jordan JE, Mays JJ, Shelton JE, Bryant AK, Lane MR, Morykwas MJ, Argenta LC.. J Card Surg. 2014;29(1):116-123.
• Interstitial-matrix edema in burns: mechanistic insights from subatmospheric pressure treatment in vivo McGee MP, Morykwas M, Campbell D, Hoge K, Argenta L.. Wound Repair Regen. 2014;22(1):96-102.
• Mechanical tissue resuscitation at the site of traumatic brain injuries reduces the volume of injury and hemorrhage in a swine model Zheng ZL, Morykwas M, Campbell D, McGee M, Hollingsworth C, Adams F, Mays J, Tatter S, Argenta L.. Neurosurgery. 2014;75(2):152-162.
• External fixation assembly and method of use Webb LX, Argenta LC, Morykwas MJ, inventors; Wake Forest University Health Sciences, assignee.. Monaco patent MC 2,094,179. 2014 Aug 1 (patent also held in Luxembourg, Italy, Ireland, France, Switzerland, Australia, Spain, and EPO). 2014;():.
• Latest trends in minimally invasive synostosis surgery: a review Sanger C, David L, Argenta L.. Curr Opin Otolaryngol Head Neck Surg. 2014;22(4):316-321.
• Water potential of cell microenvironments modulates their proliferation [abstract] McGee MP, Morykwas M, McCabe E, Kearns M, Argenta L.. Biophys J. 2014;106(2 Suppl 1):174A.
• Eradicating group A streptococcus bacteria and biofilms using functionalised multi-wall carbon nanotubes Levi-Polyachenko N, Young C, MacNeill C, Braden A, Argenta L, Reid S.. Int J Hyperthermia. 2014;30(7):490-501.
• Vacuum-assisted closure for complex cranial wounds involving the loss of dura mater Powers AK, Neal MT, Argenta LC, Wilson JA, DeFranzo AJ, Tatter SB.. J Neurosurg. 2013;118(2):302-308.
• Interstitial-matrix' fluid-fluxes in vivo: subatmospheric pressure reverses hydration-potential in heat-denatured dermis [abstract] McGee MP, Morykwas M, Hoge K, Campbell D, Argenta L.. Biophys J. 2013;104(2 Suppl 1):336A.
• Apparatus and method for wound treatment employing periodic sub-atmospheric pressure Argenta LO, Morykwas MJ, Webb LX, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 8,377,016. 2013 Feb 19. 2013;():.
• Mechanical Tissue Resuscitation (MTR) activates the RISK pathway and widens the therapeutic window for treating acute myocardial infarction [abstract] Jordan JE, Pereira BD, Morykwas MJ, Lane MR, Mays JI, Colmer G, Hollingsworth C, Argenta LC.. FASEB J. 2013;27():1130.4.
• Interstitial matrix flow-regulation: myocardial fibroblasts respond to colloidosmotic pressure [abstract] McGee MP, Morykwas M, Wang R, Jordan J, Argenta L.. Circ Res. 2013;113(4 Suppl):A061.
• A new method for modulating traumatic brain injury with mechanical tissue resuscitation Argenta LC, Zheng Z, Bryant A, Tatter SB, Morykwas MJ.. Neurosurgery. 2012;70(5):1281-1295.
• AlloDerm revision for failed pharyngoplasty Kelly DA, Plikatitis C, Blalock D, Argenta LC, David LR.. J Craniofac Surg. 2012;23(3):645-649.
• Collagen unfolding accelerates water influx, determining hydration in the interstitial matrix McGee MP, Morykwas M, Shelton J, Argenta L.. Biophys J. 2012;103(10):2157-2166.
• Influence of frontosphenoidal suture synostosis on skull dysmorphology in unicoronal suture synostosis Showalter BM, David LR, Argenta LC, Thompson JT.. J Craniofac Surg. 2012;23(6):1709-1712.
• Production of a biodegradable electrospun biomaterial with tensile strength and elasticity [abstract] Wagner WD, Argenta LC, Morykwas MJ, Levi-Polyachenko N.. FASEB J. 2012;26(Meeting Abstracts Suppl):905.2.
• Ischemia-reperfusion injury decreases myocardial hydration potential without changing flow resistance in the interstitial matrix [abstract] McGee MP, Morykwas M, Jordan J, Argenta L.. Circ Res. 2012;111(4 Suppl):235.
• Apparatus and method for wound treatment employing periodic sub-atmospheric pressure Morykwas MJ, Argenta LC, inventors; Wake Forest University Health Sciences, assignee.. Israel patent IL 199,715. 2012 Nov 1. 2012;():.
• Device and method for treating central nervous system pathology Argenta LC, Carroll DL, Levi NH, Liu J, Morykwas MJ, Tatter S, Wagner WD, inventors; Wake Forest University Health Sciences and Wake Forest University, assignees.. United States patent 8,267,960. 2012 Sept 8. 2012;():.
• Aplasia cutis congenita: clinical management of a rare congenital anomaly Bharti G, Groves L, David LR, Sanger C, Argenta LC.. J Craniofac Surg. 2011;22(1):159-165.
• Increased incidence of metopic suture abnormalities in children with positional plagiocephaly Fisher DC, Kornrumpf BP, Couture D, Glazier SS, Argenta LC, David LR.. J Craniofac Surg. 2011;22(1):89-95.
• The local pathology of interstitial edema: surface tension increases hydration potential in heat-damaged skin McGee MP, Morykwas MJ, Argenta LC.. Wound Repair Regen. 2011;19(3):358-367.
• Congenital pyriform aperture stenosis Bharti G, Groves L, Sanger C, Argenta LC.. J Craniofac Surg. 2011;22(3):992-994.
• External fixation assembly and method of use Webb LX, Argenta LC, Morykwas MJ, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 7,931,651. 2011 Apr 26. 2011;():.
• Development of a biodegradable foam for use in negative pressure wound therapy Liu J, Morykwas MJ, Argenta LC, Wagner WD.. J Biomed Mater Res B Appl Biomater. 2011;98B(2):316-322.
• Giant facial lymphangioma Sanger C, Wong L, Wood J, David LR, Argenta LC.. J Craniofac Surg. 2011;22(4):1271-1274.
• Time-dependent perioperative anesthetic management and outcomes of the first 100 consecutive cases of spring-assisted surgery for sagittal craniosynostosis Ririe DG, Smith TE, Wood BC, Glazier SS, Couture DE, Argenta LC, David LR.. Pediatr Anesth. 2011;21(10):1015-1019.
• Directed tissue growth employing reduced pressure Webb LX, Argenta LC, Morykwas MJ, inventors; Wake Forest University Health Sciences, assignee.. Sweden patent SE 1,517,660. 2011 Aug 24; (patent also held in Germany, Netherlands, Italy, United Kingdom, Austria, Spain, Ireland, Switzerland, Monaco, France, Greece, European Patent Office, Canada). 2011;():.
• Outcome analysis of our first 75 spring-assisted surgeries for scaphocephaly David LR, Plikaitis CM, Couture D, Glazier SS, Argenta LC.. J Craniofac Surg. 2010;21(1):3-9.
• Reduction of myocardial ischemia-reperfusion injury by mechanical tissue resuscitation using sub-atmospheric pressure Argenta LC, Morykwas MJ, Mays JJ, Thompson EA, Hammon JW, Jordan JE.. J Card Surg. 2010;25(2):247-252.
• Principles and applications of vacuum-assisted closure (VAC) Marks MW, Argenta LC, DeFranzo AJ. In: Weinzweig J, ed. Plastic surgery secrets. 2nd ed. Philadelphia: Mosby/Elsevier;2010: 38-44.

All Publications

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