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David E. Kram, MD

  • Find a Pediatric Specialist
  • New Patient Appointments

    Locally

    336-716-WAKE

    Toll-free

    888-716-WAKE

  • Additional Information

    For returning patient appointments, contact the clinic directly.


David E. Kram, MD

David E. Kram, MD

Assistant Professor, Pediatrics

Biomedical Informatics Comprehensive Cancer Center

Doctor Rating

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contactCONTACT & REFERRAL

Contact Information

  • New Patient Appointments:

    336-716-WAKE

  • Returning Patient Appointments:

    336-713-4500

  • Fax: 336-716-7100

  • NPI: 1114243987

Clinical Interests

  • Pediatric Hematology and Oncology, Brain Tumors

Education & Training

  • BA

    2004 - University of Florida

  • MD

    2010 - Tel Aviv University Sackler School of Medicine - Israel

  • Residency

    2013 - Pediatrics: University Connecticut Affiliated Hospitals

  • Fellowship

    2016 - Pediatric Hematology-Oncology: Oregon Health Science University School

Board Certifications

  • American Board of Pediatrics Pediatric Hematology-Oncology

  • American Board of Pediatrics Pediatrics

contactRESEARCH

Research Contact Information

  • Fax: 336-716-7100

Research Interests

  • Hypothalamus, Dexamethasone, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neurons, Signal Transduction

Recent Publications

  • Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.
    Clarke M, Mackay A, Ismer B, Pickles JC, Tatevossian RG, Newman S, Bale TA, Stoler I, Izquierdo E, Temelso S, Carvalho DM, Molinari V, Burford A, Howell L, Virasami A, Fairchild AR, Avery A, Chalker J, Kristiansen M, Haupfear K, Dalton JD, Orisme W, Wen J, Hubank M, Kurian KM, Rowe C, Maybury M, Crosier S, Knipstein J, Schüller U, Kordes U, Kram DE, Snuderl M, Bridges L, Martin AJ, Doey LJ, Al-Sarraj S, Chandler C, Zebian B, Cairns C, Natrajan R, Boult JKR, Robinson SP, Sill M, Dunkel IJ, Gilheeney SW, Rosenblum MK, Hughes D, Proszek PZ, Macdonald TJ, Preusser M, Haberler C, Slavc I, Packer R, Ng HK, Caspi S, Popovic M, Faganel Kotnik B, Wood MD, Baird L, Davare MA, Solomon DA, Olsen TK, Brandal P, Farrell M, Cryan JB, Capra M, Karremann M, Schittenhelm J, Schuhmann MU, Ebinger M, Dinjens WNM, Kerl K, Hettmer S, Pietsch T, Andreiuolo F, Driever PH, Korshunov A, Hiddingh L, Worst BC, Sturm D, Zuckermann M, Witt O, Bloom T, Mitchell C, Miele E, Colafati GS, Diomedi-Camassei F, Bailey S, Moore AS, Hassall TEG, Lowis SP, Tsoli M, Cowley MJ, Ziegler DS, Karajannis MA, Aquilina K, Hargrave DR, Carceller F, Marshall LV, von Deimling A, Kramm CM, Pfister SM, Sahm F, Baker SJ, Mastronuzzi A, Carai A, Vinci M, Capper D, Popov S, Ellison DW, Jacques TS, Jones DTW, Jones C. Cancer Discov. 2020 Jul; 10(7):942-963.
  • Tumor Lysis Syndrome.
    Russell TB, Kram DE. Pediatr Rev. 2020 Jan; 41(1):20-26.
  • Treatment of Pediatric Glioblastoma with Combination Olaparib and Temozolomide Demonstrates 2-Year Durable Response.
    Valiakhmetova A, Gorelyshev S, Konovalov A, Trunin Y, Savateev A, Kram DE, Severson E, Hemmerich A, Edgerly C, Duncan D, Britt N, Huang RSP, Elvin J, Miller V, Ross JS, Gay L, McCorkle J, Rankin A, Erlich RL, Chudnovsky Y, Ramkissoon SH. Oncologist. 2020 02; 25(2):e198-e202.
  • STX11-deficient familial hemophagocytic lymphohistiocytosis type 4 is associated with self-resolving flares and a milder clinical course.
    Kram DE, Santarelli MD, Russell TB, Pearsall KB, Saldaña BD. Pediatr Blood Cancer. 2019 09; 66(9):e27890.
  • Embryonal Tumors of the Central Nervous System in Children: The Era of Targeted Therapeutics.
    Kram DE, Henderson JJ, Baig M, Chakraborty D, Gardner MA, Biswas S, Khatua S. . 2018 Sep; 5(4)
  • Precision Neuro-oncology: the Role of Genomic Testing in the Management of Adult and Pediatric Gliomas.
    Ramkissoon LA, Britt N, Guevara A, Whitt E, Severson E, Sathyan P, Gay L, Elvin J, Ross JS, Brown C, Stogner-Underwood K, Mott R, Kram D, Strowd R, Lesser GJ, Ramkissoon SH. Curr Treat Options Oncol. 2018 06; 19(8):41.
  • Dexamethasone Chemotherapy Does Not Disrupt Orexin Signaling.
    Kram DE, Krasnow SM, Levasseur PR, Zhu X, Stork LC, Marks DL. PLoS ONE. 2016; 11(12):e0168731.
  • Bilateral conjunctival extranodal marginal zone B-cell lymphoma.
    Kram DE, Brathwaite CD, Khatib ZA. Pediatr Blood Cancer. 2010 Dec; 55(7):1414-6.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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Doctor Ratings

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contactREQUEST AN APPOINTMENT

We're sorry, Dr. Kram is not currently accepting new patients. If you are an existing patient, you may contact the office directly at 336-713-4500.

  • Find a Pediatric Specialist
  • New Patient Appointments

    Locally

    336-716-WAKE

    Toll-free

    888-716-WAKE

  • Additional Information

    For returning patient appointments, contact the clinic directly.