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  • Pediatric Nephrology
  • Request an Appointment

    New Patients

    336-716-WAKE

    Returning Patients

    336-713-4500

  • Additional Information

    Location
    7th Floor Ardmore Tower
    Medical Center Blvd
    Winston Salem, NC 27157

    Referring Providers
    If you are a provider making a referral, or wish to speak to with one of our providers, please call 336-713-4500



Pediatric Hypertension - Research and Innovation

Our goal is to be a national leader in the care of children, adolescents and young adults who have hypertension and hypertensive conditions. We have an exceptionally strong and diverse team of investigators and students involved in several ongoing clinical and translational research studies to help us better understand why and how hypertension develops in the first place, how best to treat it, how it causes organ damage and how it affects your child’s future health as an adult.

We are studying the role of numerous factors in hypertension, including health disparities (such as food insecurity), uric acid, vitamin D and the renin-angiotensin system (a hormone system that is an important regulator of blood pressure). We are also interested in how hypertension affects specific patients such as those with obesity, sickle cell disease, neurologic (brain) conditions, mental and behavioral health conditions including ADD/ADHD and autonomic dysfunction (postural orthostatic tachycardia syndrome). Our patients and their families are important to the success of our research efforts, without whom none of it would be possible.

Learn more about our active studies and how you can get involved.

  • The Pediatric Hypertension Registry allows us to study our patients who have hypertension and is now a multicenter collaboration
  • In the PHRAS study we are evaluating various markers of hypertension severity and treatment response to help guide our management

We participate in many national, multicenter studies:

  • The Neonatal Kidney Collaborative allows us to study how preterm birth, low birth weight and other early-life events lead to hypertension, cardiovascular disease and kidney disease
    The Pediatric Nephrology Research Consortium allows us to study hypertension across North America and how it affects patients with kidney diseases, those who are on dialysis and those who have received kidney transplants
  • The Pediatric Nephrology Research Consortium allows us to study hypertension across North America and how it affects patients with kidney diseases, those who are on dialysis and those who have received kidney transplants
  • The SEARCH for Diabetes in Youth Study allows us to study hypertension in patients who have type 1 and type 2 diabetes

We use several state-of-the-art tests to determine how hypertension affects the body:

  • Carotid intima-media thickness to look at how thick blood vessel walls are
  • Vascular stiffness (pulse wave velocity, augmentation index) to look at the stiffness of the blood vessels
  • Nailfold capillaroscopy
  • Autonomic function (heart rate variability, baroreflex sensitivity) to measure how the brain controls blood pressure

Read more about what we have learned so far.

Collaboration at Wake Forest

We collaborate with various centers and institutes at Wake Forest to advance our knowledge of hypertension and cardiovascular disease in children, adolescents and young adults.

  • Pediatric Nephrology
  • Request an Appointment

    New Patients

    336-716-WAKE

    Returning Patients

    336-713-4500

  • Additional Information

    Location
    7th Floor Ardmore Tower
    Medical Center Blvd
    Winston Salem, NC 27157

    Referring Providers
    If you are a provider making a referral, or wish to speak to with one of our providers, please call 336-713-4500